GAS41 YEATS Domain, Recombinant Human
Catalogue Number: 15-0075-EPC
15-0075 Image
15-0075 Image
15-0075 Image
Figure 1: Protein gel data GAS41 YEATS Domain (1 µg) was resolved via PAGE gel and stained with Coomassie blue to demonstrate the size and purity of the protein. The migration and molecular weight of the protein standards are indicated.
15-0075 Image
Figure 2: Protein interaction data GAS41 YEATS Domain demonstrates preferential binding to H3K9cr, followed by H3K9,14,18cr and H3K9ac. There was no significant binding to H3(1-20) control peptide when analyzed by AlphaScreen® (PerkinElmer). All peptides assayed at 100 nM.
| Manufacturer: | EpiCypher |
| Shelf Life: | 6 months |
| Molecular Weight: | 19.3 kDa |
| Ph: | 7.5 |
| Type: | DNA Binding Proteins |
| Host Cell: | E.coli |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug |
Description
Description: GAS41 YEATS Domain (accession O95619, amino acids 15-160) expressed in E. coli containing an N-terminal 6xHis tag. The GAS41 protein is part of the NuA4 histone acetyltransferase complex, which is involved with the activation of genes via acetylation of histones H4 and H2A [1]. GAS41 YEATS Domain recognizes and binds acetylated and crotonylated histone H3 [2].
Additional Text
Gene ID
8089
Gene Name
YEATS4
Uniprot ID
O95619
Protein Tag
HIS Tag
Application Notes
GAS41 YEATS Domain is useful for protein binding and screening experiments examining acetylated and crotonylated protein substrates.
Storage Note
Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.
15-0075 Datasheet
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