Imidazoquinoline Resiquimod (R-848)
Catalogue Number: 15-1016-ABO
| Manufacturer: | Abeomics |
| Type: | Ligand |
| Alias: | Resiquimod; S 28463; R848 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 500 ug |
| Application: | FA |
Description
Description: Formula: C17H22N4O2 MW: 314.4 Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines, potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kB, NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I.Upregulator of the opioid growth factor receptor. Used in the treatment of skin lesions such as herpes simplex virus.
Additional Text
Application Notes
Solubility: Soluble in DMSO, dichloromethane or methanol. Slightly soluble in acetonitrile or ethyl acetate.
Storage Note
Store the product at 4°C for short term and at -20°C for long-term storage. Product is stable for 2 years at -20°C.
15-1016 Datasheet
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