Imidazoquinoline Resiquimod (R-848)

Catalogue Number: 15-1016-ABO

Manufacturer:Abeomics
Type:Ligand
Alias:Resiquimod; S 28463; R848
Shipping Condition:Blue Ice
Unit(s): 1 mg, 500 ug
Application: FA

Description

Description: Formula: C17H22N4O2 MW: 314.4 Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines, potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kB, NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I.Upregulator of the opioid growth factor receptor. Used in the treatment of skin lesions such as herpes simplex virus.

Additional Text

Application Notes

Solubility: Soluble in DMSO, dichloromethane or methanol. Slightly soluble in acetonitrile or ethyl acetate.

Storage Note

Store the product at 4°C for short term and at -20°C for long-term storage. Product is stable for 2 years at -20°C.