Catalogue Number: 16-05-030112-ART
Manufacturer: | Athens Research |
Preservative: | Frozen in 20 mM imidazole, 5mM β-mercaptoethanol, 1 mM EDTA, 1mM EGTA, 30% glycerol, pH 6.8 |
Molecular Weight: | 110,000 Daltons |
Ph: | ph 6.8 |
Physical state: | Frozen |
Type: | Proteases |
Shipping Condition: | Dry Ice |
Storage Condition: | -70°C |
Unit(s): | 100 ug, 500 ug |
Description: Calpain-1 (µ-Calpain) is a calcium activated neutral cysteine protease. It is a heterodimer of a Catalytic 80 kDa subunit and a 30 kDa subunit, which requires 50 µM Ca2+ for half-maximal activity in vitro. Its participation in events such as cell division, signal transduction, and long term potentiation has been suggested. Calpains have also been proposed to play a role in various pathological processes associated with altered metabolism and altered calcium homeostasis.