Histone Variant H2AZ.1 Recombinant Nucleosome, Non-Biotinylated
Catalogue Number: 16-1014-EPC
| Manufacturer: | EpiCypher |
| Shelf Life: | 6 months |
| Type: | Nucleosome |
| Host Cell: | E. coli & synthetic DNA|Human |
| Shipping Condition: | Dry Ice |
| Unit(s): | 50 ug |
| Host name: | Human |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: Histone Variant H2AZ.1 Recombinant Nucleosome, Non-Biotinylated consists of 147 base pairs of 601 sequence DNA [1] wrapped around an octamer core of histone proteins (two each of H2AZ.1, H2B, H3.1, and H4) to form a nucleosome, the basic repeating unit of chromatin. H2AZ.1 and H2AZ.2 are isoforms of the H2A.Z variant of histone H2A and are implicated in diverse cellular functions such as transcriptional regulation, chromosome transmission, and DNA damage repair. H2AZ has a dedicated deposition machinery (the SWR-C ATPase) [2].
Additional Text
Protein Tag
Untagged
Storage Note
Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.
Application Notes
Histone Variant H2AZ.1 Nucleosome is highly purified and suitable for a variety of applications, including use as a substrate in enzyme assays, high-throughput screening and inhibitor testing, chromatin binding studies, protein-protein interaction assays, structural studies, and in effector protein binding experiments. The absence of post-translational histone modifications makes this nucleosome ideal for conducting enzyme activity and screening assays.
16-1014 Datasheet
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