Nucleosome, Recombinant Human, H3S10phos dNuc, Non-Biotinylated
Catalogue Number: 16-1345-EPC
| Manufacturer: | EpiCypher |
| Shelf Life: | 6 months |
| Type: | Nucleosome |
| Host Cell: | E. coli & synthetic DNA|Human |
| Shipping Condition: | Dry Ice |
| Unit(s): | 50 ug |
| Host name: | Human |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: Recombinant mononucleosomes (H3S10phos) consist of 147 base pairs of DNA wrapped around an octamer core of histone proteins (two each of H2A, H2B, H3.1, and H4) to form a nucleosome, the basic repeating unit of chromatin. The 147 bp 601 sequence, identified by Lowary and Widom [1], has high affinity for histone octamers and is useful for nucleosome assembly. H3S10phos dNuc contains phosphorylated serine at position 10 on histone H3.1.
Additional Text
Modification
Phosphorylated, Ser10
Protein Tag
Untagged
Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws
Application Notes
H3S10phos mononucleosome is highly purified and suitable for a variety of applications, including use as a substrate in enzyme assays, high-throughput screening and inhibitor testing, chromatin binding studies, protein-protein interaction assays, structural studies, and in effector protein binding experiments.
16-1345 Datasheet
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