Catalogue Number: 16-14-021609-ART
Manufacturer: | Athens Research |
Preservative: | Frozen in 80 mM Citrate Phosphate, pH 5.6, 700-750 mM NaCl. |
Molecular Weight: | 55000 |
Ph: | pH 5.6 |
Physical state: | Frozen |
Type: | Protease Inhibitor Protein |
Shipping Condition: | Dry Ice |
Storage Condition: | -70°C |
Unit(s): | 100 ug |
Description: Bacterial/Permeability-Increasing Protein (BPI) is present in the azurophilic granules of polymorphonuclear leukocytes (PMN). BPI is toxic only toward Gram-negative bacteria. This specificity is attributable to the strong attraction of BPI for the lipopolysaccharides (LPS) in the bacterial envelope. BPI is also an important antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in vasculitis.