G-C Globulin (Vitamin D Binding Protein)
Catalogue Number: 16-16-070307-ART
16-16-070307 Image
16-16-070307 Image
SDS-PAGE: 4-12% Bis-Tris-HCl NuPAGE gel 1. GC Globulin - 5 µg (reduced / heated) 2. GC Globulin - 10 µg (reduced / heated) 3. GC Globulin - 20 µg (reduced / heated) 4. LMW Standard (BIO-RAD Cat. No. 161-0304) 5. GC Globulin - 5 µg (non-reduced / no heat) 6. GC Globulin - 10 µg (non-reduced / no heat) 7. GC Globulin - 20 µg (non-reduced / no heat)
| Manufacturer: | Athens Research |
| Preservative: | Lyophilized from 20 mM Na phosphate, pH 7.4, with 150 mM NaCl. |
| Molecular Weight: | 56,000 Da |
| Ph: | ph 7.4 |
| Physical state: | Lyophilized |
| Type: | Other Proteins |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg |
Description
Description: An alpha 2 glycoprotein composed of a single polypeptide chain and present in plasma at levels of 20-55 mg/100 ml. It functions in the binding and transport of vitamin D and may also play an important role in actin homeostatis since it has been shown to bind monomeric actin with high affinity. GC-globulin also binds membranes of both circulating B and T lymphocytes. Clinically, concentrations are reduced in patients with severe liver diseases. GC-globulin may also play an important role in the mechanism of the osteomalacia that occurs with Itai-Itai disease.
16-16-070307 Datasheet
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