Inter Alpha Inhibitor Protein (IAIP), Human Plasma
Catalogue Number: 16-16-090109-ART
| Manufacturer: | Athens Research |
| Preservative: | Frozen in 1 x PBS |
| Molecular Weight: | 225,000 and 125,000 Da |
| Physical state: | Frozen |
| Type: | Protease Inhibitor Protein |
| Shipping Condition: | Dry Ice |
| Storage Condition: | -70°C |
| Unit(s): | 1 mg, 100 ug, 25 ug |
Description
Description: Inter Alpha Inhibitor Proteins (IaIp)- include Inter Alpha Trypsin Inhibitor (IaI) and Pre Alpha Inhibitor (Pal), with molecular weights of 225 kDa and 125 kDa respectively. Together these proteins are present in plasma at a concentration of approximately 50 mg/100 ml. The inhibitory activity of the proteins is a function of bikunin, the common light chain of the IAIP. In acute inflammation, the lal acts as a negative acute-phase protein, whereas the Pal acts as a positive acute-phase protein. IaIp are being considered as biomarkers and biotherapies for metastatic disease, septic shock and complement system disorders.
16-16-090109 Datasheet
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