Catalogue Number: 16-16-090707-3-ART
Manufacturer: | Athens Research |
Preservative: | Liquid in 20 mM phosphate, pH 7.4, with 150 mM NaCl and 0.05% NaN3. |
Molecular Weight: | 170,000 Da |
Ph: | ph 7.4 |
Physical state: | Liquid |
Type: | Immunoglobulins |
Shipping Condition: | Blue Ice |
Storage Condition: | 2-8°C |
Unit(s): | 1 mg |
Description: Like IgG1, IgG3 activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection.