Catalogue Number: 16-16-110914-H-ART
Manufacturer: | Athens Research |
Preservative: | Frozen in 10 mM Na acetate, pH 5.5, with 250 mM NaCl |
Molecular Weight: | 120000 |
Ph: | pH 5.5 |
Physical state: | Frozen |
Type: | Protease Inhibitor Protein |
Shipping Condition: | Dry Ice |
Unit(s): | 100 ug |
Description: High Molecular Weight kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a cofactor in the activation of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease.