TGF-Beta-1 EIA, 96 wells, "RUO"
Catalogue Number: 20-TGF1HU-E01-ALP
| Manufacturer: | Alpco Diagnostics |
| Type: | Human ELISA Kit |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 96 Wells |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Range: | 19 - 600 pg/mL |
| Sensitivity: | 1.9 pg/mL |
| Sample type: | Cell Culture, Serum |
| Sample size: | 10 µL |
| Application: | IA, EIA |
Description
Description: Transforming Growth Factor β1 (TGF-β1) is a 25 kDa homodimer composed of two 12.5 kDasubunits joined by disulfide bonds (1). TGF-β1 is a multipotent cytokine with cell- and dosedependent activities. This molecule is produced by a number of cells and tissue types, e.g.thrombocytes, bone tissue, placenta and kidneys. This potent cytokine modulates embryonicdevelopment, bone formation, mammary development, wound healing, hematopoiesis, cell cycleprogression and the production of the extracellular matrix. With respect to the immune system,TGF-β1 inhibits T and B cell proliferation and acts as an anti-inflammatory molecule both in vitroand in vivo. TGF-β1 inhibits macrophage maturation and activation. This molecule also inhibitsthe activity of natural killer cells and lymphokine activated killer cells and blocks cytokineproduction.
Additional Text
Regulatory Statuses
FDA Registered. For In Vitro Diagnostic Use.
Short Description
The TGF Beta-1 ELISA is an enzyme immunoassay for the quantitative in vitro diagnostic measurement of TGF-β1 in serum and cell culture supernatant.
Storage Note
store at 2-8C
20-TGF1HU-E01 Protocol
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