Wheat Germ Agglutinin, XFD488 Labeled *XFD488 Same Structure to Alexa Fluor™ 488*

Catalogue Number: 25500-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Other Proteins
Shipping Condition:RT
Unit(s): 1 mg

Description

Description: XFD488 is manufactured by AAT Bioquest, and it has the same chemical structure of Alexa Fluor® 488 (Alexa Fluor® is the trademark of ThermoFisher). Wheat germ agglutinin (WGA) is a lectin that binds to N-acetyl-D-glucosamine and sialic acid. It is of the most studied and useful lectins for its biological applications. Since WGA binds to glycoconjugates its derivatives and conjugates are widely used to label cell membranes and fibrotic scar tissue for fluorescence imaging and analysis. The carbohydrate-binding specificity of WGA is directed against sequences of β-1,4-GlcNAc-linked residues, the chitodextrins. Each monomer contains two identical, non-interacting binding sites, which are complementary to 3 or 4 β-1,4-GlcNAc units. Of the monosaccharides examined, only GlcNAc binds to WGA. ManNAc does not bind, and GalNAc binds only weakly. XFD488 conjugate of WGA is equivalent to the Alexa Fluor® 488 conjugate of WGA. It exhibits bright, green fluorescence. XFD488 WGA conjugate binds to sialic acid and N-acetylglucosaminyl residues.

Additional Text

Storage Note

Freeze (< -15 °C); Minimize light exposure;|12 months