Human CD134/OX40 Assay Kit 27110

Catalogue Number: 27110-IBL

Manufacturer:	IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:	Human ELISA Kit
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	96 well plate
Range:	15.6 ~ 1,000 pg/mL
Sensitivity:
Sample type:	Cell Culture Supernatant, Plasma, Serum
Sample size:

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Datasheets

Description

Description: CD134/OX40 is a receptor of OX40 ligand (OX40L) transactivated by Tax of HTLV-1. OX40 is expressed in activated CD4+ and CD8+ T cells. OX40 on the activated T cells have a role in proliferation of T cells and production of cytokines by binding with OX40L expressed on antigen presenting cells like dendritic cells or activated B cells. In addition, it also be involved in activated T cell invasion to inflamed area through the binding with OX40L. It has been observed that soluble CD134 / OX40 in plasma is significantly higher in acute adult T-cell leukemia patients compare to HTLV-1 carriers and healthy individual in recent study. It has also been reported that HTLV-1 gene (number of the copy) in peripheral blood lymphocytes was correlated with soluble OX40 level in plasma of HTLV-1 infected patients. (See reference below) Tanaka Y, Takahashi Y, Tanaka R, Miyagi T, Saito M, Fukushima T. Association of high levels of plasma OX40 with acute adult T-cell leukemia. Int J Hematol. 2019 Jan 16.

27110 Datasheet

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£591.00

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