Catalogue Number: 27182-IBL
Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
Type: | Human ELISA Kit |
Shipping Condition: | Blue Ice |
Storage Condition: | 2-8°C |
Unit(s): | 96 well plate |
Range: | 31.25 ~ 2,000 pg/mL |
Sensitivity: | |
Sample type: | Cell Culture Supernatant, Plasma, Serum |
Sample size: |
Description: Endothelial Lipase (EL) is a metabolic enzyme of HDL. It is phospholipase A1 molecule that is high substrate specificity against to phospholipid that exists in high density lipoprotein, HDL molecule and it promotes HDL metabolism through metabolizing HDL phospholipid. It has been considered that EL involves with lipid metabolism and elevating risk of arteriosclerosis as strong expression of EL on newly formed vessel, macrophage in arteriosclerotic lesions is observed while EL expresses in vascular endothelial cells and vascular smooth myocytes of normal blood vessels. It has been reported that both full length EL (active form) and cleaved EL (inactive forms, 40K fragment cleaved at N terminal and 28K fragment cleaved at C terminal cleaved by proprotein convertase) exist in blood. This ELISA kit is designed by using two antibodies that detects N-terminal fragment and C terminal fragment so that it can detect full length EL in serum and EDTA-plasma regardless with or without administration of heparin injection that is conventionally required for the measurement. The control set is available for sale on request. Keywords: Lipase / Lipid Metabolism / Dyslipidemia