Human Amyloidβ (1-38) (FL) Assay Kit 27717

Catalogue Number: 27717-IBL

Manufacturer:	IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:	Human ELISA Kit
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	96 well plate
Range:	9.38 ~ 600 pg/mL
Sensitivity:
Sample type:	Cell Culture Supernatant, Cerebrospinal Fluid
Sample size:

Overview
Datasheets

Description

Description: The first case of Alzheimer's disease (AD) was defined and reported in 1907 by the German scientist, Dr. A. Alzheimer. His studies have shown that this is the main cause of dementia in the elderly. The plaques which appear in the brains of individuals who suffer AD are mostly constituted by the Amyloidβ protein (Aβ). Aβ is a peptide which consists of 40 or 42 (43) amino acids, and reports show that this is cleaved from β- and γ- secretase from the amyloid precursor protein. APP is a trans-membrane protein consisting of 695, 751, or 770 amino acids. Reports have shown many variants of Aβ exist and are clarified into the culture supernatant from the APP cDNA transfected mouse neuroblastoma cell. In 2001, Edward H. Koo et al. found that the secretion of Aβ42 decreased by the effect of NSAIDs, and with this, the secretion of Aβ38 increased. NSAIDs is attracting attention as a γ- secretase modulation and then Aβ38 and Aβ42 have become important object molecules to be measured as indicators for the effect of NSAIDs. This ELISA kit can measure Human Aβ (1-38) which held N-terminal side completely. IBL has many other kinds of Amyloidβ-related products for AD research. They are very specific assay systems for each target and they can be used according to the purpose of study. The control set is available for sale on request. Keywords: Alzheimer's Disease / Amyloid β / Amyloid-β / Amyloid Beta / Aβ / Beta Amyloid

27717 Datasheet

Price

£515.00

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