Anti-VCP Monoclonal Antibody (Clone:Hs-14)

Catalogue Number: 30-1188-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:VCPKMT, C14orf138, METTL21D
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Mouse
Clone: Hs-14
Isotype: IgM
Immunogen: Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.
Application: FACS, ICC, WB

Description

Description: VCP (valosin-containing protein), also known as p97, TERA, ALS14, IBMPFD, HEL-220, IBMPFD1, or HEL-S-70, is a member of a protein family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. VCP is a structural protein that associates with clathrin and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. In sperm this intra-acrosomal protein can be used as a marker for evaluation of the physiological state of sperm cells as well as for selection of a suitable method of fertilization in the laboratories of assisted reproduction.

Additional Text

Gene Name

VCPKMT

Uniprot ID

Q9H867

Storage Note

Store at 2-8°C. Do not freeze.

Gene ID

79609

Purification

Purified

Antibody Clonality

Monoclonal