Anti-Nitrotyrosine Monoclonal Antibody (Clone:EM-30)

Catalogue Number: 30-1495-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Mouse
Clone: EM-30
Isotype: IgG1
Immunogen: NO2-Tyr-CH2-Thyroglobulin
Application: WB

Description

Description: Nitrotyrosine can be detected in proteins from a variety of tissues usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage.

Additional Text

Storage Note

Store at 2-8°C. Do not freeze.

Purification

Protein A purified

Antibody Clonality

Monoclonal

Application Notes

Immunohistochemistry Recommended dilution:10 µg/ml Positive tissue:colon cancer epithelium, prostate hyperplasia