Anti-PCLO Monoclonal Antibody (Clone:PCLO-01)

Catalogue Number: 30-1500-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:PCLO||ACZ||KIAA0559
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Mouse
Clone: PCLO-01
Isotype: IgG1
Immunogen: Human recombinant PCLO protein
Application: FACS, WB

Description

Description: PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion.

Additional Text

Storage Note

Store at 2-8°C. Do not freeze.

Gene ID

27445

Purification

Protein A purified

Gene Name

Pclo

Antibody Clonality

Monoclonal

UniProt ID

Q9Y6V0