Anti-PDE8a Monoclonal Antibody (Clone:EM-52)

Catalogue Number: 30-1511-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:PDE8A
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Mouse
Clone: EM-52
Isotype: IgG1
Immunogen: Human PDE8a
Application: WB

Description

Description: PDE8a (high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 A) is a cyclic nucleotide phosphodiesterase, which hydrolyzes cAMP, an important regulator and mediator of multiple cellular responses to extracellular signals. It is expressed in a wide variety of tissues including testis, ovary, small intestine, and colon. It is not expressed e.g. in thymus. PDE8a is composed of C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.

Additional Text

Gene Name

PDE8A

Storage Note

Store at 2-8°C. Do not freeze.

Uniprot ID

O60658

Gene ID

5151

Purification

Protein A purified

Antibody Clonality

Monoclonal

Application Notes

Western blotting: Recommended dilution: 1-2 µg/ml.