Anti-AGPS Monoclonal Antibody (Clone:AGPS-03)

Catalogue Number: 30-1533-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:AGPS||AAG5
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name: Mouse
Clone: AGPS-03
Isotype: IgG2a
Immunogen: recombinant human AGPS (amino acids 158-384)
Application: FACS, WB

Description

Description: AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.

Additional Text

Gene Name

AGPS

Storage Note

Store at 2-8°C. Do not freeze.

Uniprot ID

O00116

Gene ID

8540

Purification

Protein A purified

Antibody Clonality

Monoclonal