Catalogue Number: 30-1977-ABO
Manufacturer: | Abeomics |
Type: | Monoclonal Primary Antibody - Conjugated |
Alias: | VCPKMT, C14orf138, METTL21D |
Shipping Condition: | Blue Ice |
Unit(s): | 50 tests |
Host name: | Mouse |
Clone: | Hs-14 |
Isotype: | IgM |
Immunogen: | Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization. |
Application: | FACS |
Description: VCP (valosin-containing protein), also known as p97, TERA, ALS14, IBMPFD, HEL-220, IBMPFD1, or HEL-S-70, is a member of a protein family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. VCP is a structural protein that associates with clathrin and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. In sperm this intra-acrosomal protein can be used as a marker for evaluation of the physiological state of sperm cells as well as for selection of a suitable method of fertilization in the laboratories of assisted reproduction.
VCPKMT
Q9H867
79609
Monoclonal
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.