FITC Conjugated Anti-VCP Monoclonal Antibody (Clone:Hs-14)

Catalogue Number: 30-1977-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Conjugated
Alias:VCPKMT, C14orf138, METTL21D
Shipping Condition:Blue Ice
Unit(s): 50 tests
Host name: Mouse
Clone: Hs-14
Isotype: IgM
Immunogen: Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.
Application: FACS

Description

Description: VCP (valosin-containing protein), also known as p97, TERA, ALS14, IBMPFD, HEL-220, IBMPFD1, or HEL-S-70, is a member of a protein family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. VCP is a structural protein that associates with clathrin and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. In sperm this intra-acrosomal protein can be used as a marker for evaluation of the physiological state of sperm cells as well as for selection of a suitable method of fertilization in the laboratories of assisted reproduction.

Additional Text

Gene Name

VCPKMT

Uniprot ID

Q9H867

Gene ID

79609

Antibody Clonality

Monoclonal

Storage Note

Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.