PerCP Conjugated, Anti-CD15 / Lewis x Blood Group antigen Monoclonal Antibody (Clone:MEM-158)
Catalogue Number: 30-2423-ABO
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CDRT15L2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | MEM-158 |
| Isotype: | IgM |
| Immunogen: | Human granulocytes |
| Application: | FACS |
Description
Description: CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
Additional Text
Gene ID
256223
Gene Name
CDRT15L2
Uniprot ID
A8MXV6
Antibody Clonality
Monoclonal
Storage Note
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
30-2423 Datasheet
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