Anti-HDAC6 Antibody (Clone : 159)
Catalogue Number: 30-2525-ABO
30-2525 Image
30-2525 Image
Figure 1 : Separation of K562 cells stained using anti-HDAC6 (159) purified antibody (concentration in sample 4,0 µg/ml, GAM APC, red-filled) from K562 cells unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (intracellular staining).
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Histone deacetylase 6,histone deacetylase 6 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | |
| Clone: | 159 |
| Isotype: | IgG1, kappa |
| Immunogen: | human HDAC6 |
| Application: | ELISA, FACS, ICC, WB |
Description
Description: Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.Specificity : The mouse monoclonal antibody 159 recognizes SE domain of human histone deacetylase 6 (HDAC6; an intracellular antigen), amino acids 971-981. Crossreactivity with other species was not tested.
Additional Text
Gene Name
HDAC6
Gene ID
10013
Storage Note
Store at 2-8°C. Do not freeze.
Purification
Protein A purified
Antibody Clonality
Monoclonal
Application Notes
Flow cytometry: Recommended dilution: 1-4 µg/ml
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