Anti-HDAC6 Antibody (Clone : 236)

Catalogue Number: 30-2527-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Histone deacetylase 6,histone deacetylase 6
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name:
Clone: 236
Isotype: IgG2b, kappa
Immunogen: human HDAC6
Application: ELISA, ICC, IP, WB

Description

Description: Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.Specificity : The mouse monoclonal antibody 236 recognizes D1 domain of human histone deacetylase 6 (HDAC6; intracellular antigen), amino acids 71-91. Crossreactivity with other species was not tested.

Additional Text

Gene Name

HDAC6

Gene ID

10013

Storage Note

Store at 2-8°C. Do not freeze.

Purification

Protein A purified

Antibody Clonality

Monoclonal