Anti-HDAC6 Antibody (Clone : 236)
Catalogue Number: 30-2527-ABO
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Histone deacetylase 6,histone deacetylase 6 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.1 mg |
| Host name: | |
| Clone: | 236 |
| Isotype: | IgG2b, kappa |
| Immunogen: | human HDAC6 |
| Application: | ELISA, ICC, IP, WB |
Description
Description: Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.Specificity : The mouse monoclonal antibody 236 recognizes D1 domain of human histone deacetylase 6 (HDAC6; intracellular antigen), amino acids 71-91. Crossreactivity with other species was not tested.
Additional Text
Gene Name
HDAC6
Gene ID
10013
Storage Note
Store at 2-8°C. Do not freeze.
Purification
Protein A purified
Antibody Clonality
Monoclonal
30-2527 Datasheet
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