Anti-DLL4 PE (Clone : MHD4-46)

Catalogue Number: 30-2532-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Conjugated
Alias:Delta like ligand 4, AOS6, canonical Notch ligand 4,delta like canonical Notch ligand 4
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name:
Clone: MHD4-46
Isotype: IgG1, kappa
Immunogen: recombinant soluble human DLL4
Application: FACS

Description

Description: DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.Specificity : The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.

Additional Text

Gene ID

54567

Gene Name

DLL4

Purification

Purified

Antibody Clonality

Monoclonal

Storage Note

Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.