Anti-TAp63 Purified

Catalogue Number: 30-2718-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Alias:tumor protein p63 AIS, KET, LMS, NBP, RHS, EEC3, OFC8, SHFM4
Shipping Condition:Blue Ice
Unit(s): 0.1 mg
Host name:
Clone: TAp63-4.1
Isotype:
Immunogen: Recombinant human p63
Application: ICC, IP, WB, IHC

Description

Description: The p53 family of proteins includes three members, p53, p63, and p73. The protein p63 is encoded by TP63 gene, which gives rise to protein isoforms with different properties and functions due to the presence (TAp63) or absence (deltaNp63) of an N-terminal transactivation domain. Immunohistochemistry of p63 has a clinical relevance for certain tumor types, but investigations have been hampered by a lack of well characterized antibodies that are specific for p63, do not cross-react with the related p53 and p73 proteins, and allow for discrimination between p63 isoforms TAp63 and deltaNp63 with opposite functional properties.Specificity :The mouse monoclonal antibody TAp63-4.1 recognizes TAp63; target epitope LSDPMW. This antibody does not bind to deltaNp63 isoform of p63.

Additional Text

Gene Name

TP63

Gene ID

8626

Uniprot ID

Q9H3D4

Storage Note

Store at 2-8°C. Do not freeze.

Purification

Protein A purified

Antibody Clonality

Monoclonal

Application Notes

Western blotting: Recommended dilution: 1 µg/ml