Mouse Anti-Human GFAP-Biotin Conjugated

Catalogue Number: 31-3758-ABO

Manufacturer:	Abeomics
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	GFAP
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	0.5 mg
Host name:
Clone:	SB61b
Isotype:	IgG2b, kappa
Immunogen:
Application:	ELISA, WB, IHC-Fr, IHC

Overview
Datasheets

Description

Description: Glial fibrillary acid protein (GFAP) is a member of the type III intermediate filament family of proteins. GFAP is heavily expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and functions of the cella's cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cell; however, its precise function remains poorly understood. In adults, GFAP levels increase in response to the proliferation of astrocytes associated with Alzheimera's disease, epilepsy, and multiple sclerosis. Antibodies specific for GFAP are useful as markers of astrocytic cells and neural stem cells as well as for distinguishing neoplasms of astrocytic origin from other neoplasms in the central nervous system.

Additional Text

Gene Name

GFAP

Gene ID

2670

Storage Note

Store at 2-8°C

Uniprot ID

P14136

Antibody Clonality

Monoclonal

31-3758 Datasheet

31-3758 MSDS

Price

£510.00

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Quantity
Unit Size

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