Rabbit polyclonal antibody to SARS-CoV2 S-protein (ACE2 binding domain)

Catalogue Number: 34-1136-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype:
Immunogen:
Application: ICC, IF, WB

Description

Description: This antibody was raised against a recombinant construct of the SARS-CoV-2 spike or S-protein which includes the entire region which interacts with ACE2. The specific binding to ACE2 is essential for viral internalization and infection. We designed this construct based on amino acids 308-541 in the S-protein sequence in Isolate Wuhan-Hu-1, complete genome. This is a defined globular domain recently shown to include all of the amino acids necessary for ACE2 binding. The construct was expressed in and purified from E. coli and includes an N-terminal His-tag and other vector derived sequence shown underlined below. Amino acids which interact directly with the ACE2 protein are printed in bold.

Additional Text

Antibody Clonality

Polyclonal

Application Notes

WB: 1:1,000-1:2,000. ICC/IF: 1:3,000-5,000

Storage Note

Store at 4°C for short term, for longer term at -20°C. Avoid freeze / thaw cycles.