Polyclonal Antibody to NF-kB-p105/p50(Phospho-Ser893)

Catalogue Number: 35-1017-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:KBF1|| NF-kB1|| NFkappaB
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide sequence around aa.891~895 (A-S-S-P-V) derived from Human NF-kB-p105.
Application: IF, IHC

Description

Description: NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NF-kB1/p105, NF-kB1/p50, REL and NF-kB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

Additional Text

Gene Name

NFKB1

Gene ID

4790

Uniprot ID

P19838

Antibody Clonality

Polyclonal

Application Notes

Immunohistochemistry 1:50~1:100 Immunofluorescence 1:100~1:200

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.