Polyclonal Antibody to HDAC8 (Phospho-Ser39)

Catalogue Number: 35-1124-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:HD8|| HDA8|| HDACL1
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8.
Application: IF, IHC

Description

Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Additional Text

Gene Name

HDAC8

Gene ID

55869

Uniprot ID

Q9BY41

Antibody Clonality

Polyclonal

Application Notes

Predicted MW: 42kd, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.