Polyclonal Antibody to HDAC8 (Phospho-Ser39)
Catalogue Number: 35-1124-ABO
35-1124 Image
35-1124 Image
35-1124 Image
Figure 1: Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using HDAC8(Phospho-Ser39) Antibody 35-1124 (left) or the same antibody preincubated with blocking peptide(right).
35-1124 Image
Figure 2: Immunofluorescence staining of methanol-fixed Hela cells using HDAC8(Phospho-Ser39) Antibody 35-1124 .
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | HD8|| HDA8|| HDACL1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8. |
| Application: | IF, IHC |
Description
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Additional Text
Gene Name
HDAC8
Gene ID
55869
Uniprot ID
Q9BY41
Antibody Clonality
Polyclonal
Application Notes
Predicted MW: 42kd, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
35-1124 Datasheet
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