Polyclonal Antibody to IkB- Alpha (Phospho-Tyr42) Antibody
Catalogue Number: 35-1155-ABO
35-1155 Image
35-1155 Image
35-1155 Image
Figure 1: Western blot analysis of extract from Hela cells untreated or treated with serum using IkB-a(Phospho-Tyr42) Antibody 35-1155 .
35-1155 Image
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using IkB-a(phospho-Tyr42) antibody(35-1155 ).
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | IkBA, MAD-3, NF-kBI, NF-kBIA |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide sequence around phosphorylation site of tyrosine 42 (E-E-Y(p)-E-Q) derived from Human IkB-a |
| Application: | WB, IHC |
Description
Description: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription.
Additional Text
Gene ID
4792
Gene Name
NFKBIA
Uniprot ID
P25963
Antibody Clonality
Polyclonal
Application Notes
Predicted MW: 39kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
35-1155 Datasheet
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