Polyclonal Antibody to Histone H3 (Phospho-Thr11)

Catalogue Number: 35-1342-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:H3/a H3/m H3.3A|| H3/c H3/o H3F3B|| H3/d|| H3/f|| H3/h
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide sequence around phosphorylation site of threonine 11(K-S-T(p)-G-G) derived from Human Histone H3.
Application: WB

Description

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Additional Text

Antibody Clonality

Polyclonal

Application Notes

Predicted MW: 17kd, Western blotting: 1:500~1:1000

UniProt ID

P68431, Q71DI3

Gene ID

126961; 333932; 653604; 8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968

Gene Name

H3C1, H3C10, H3C11, H3C12, H3C13, H3C14, H3C15, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.