Polyclonal Antibody to NF-kB-p100/p52 (Ab-866)
Catalogue Number: 35-1372-ABO
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35-1372 Image
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Figure 1: Western blot analysis of extracts from HT29 cells using NF-kB-p100(Ab-866) Antibody 35-1372 .
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Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NF-kB-p100(Ab-866) Antibody 35-1372 (left) or the same antibody preincubated with blocking peptide(right).
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Figure 3: Immunofluorescence staining of methanol-fixed Hela cells using NF-kB-p100(Ab-866) Antibody 35-1372 .
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | DNA-binding factor KBF2|| H2TF1|| Lymphocyte translocation chromosome 10|| Lyt10|| NF-kB2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide sequence around aa.864~868 (E-D-S-A-Y) derived from Human NF-kB-p100. |
| Application: | IF, WB, IHC |
Description
Description: NF-kB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NF-kB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. Qu Z, et al. (2004) J Biol Chem. 279(43): 44563-44572. Xiao G, et al. (2001) Mol Cell. 7(2): 401-409. Baeuerle P A, et al. (1994) Annu Rev Immunol. 12:141-179. Baeuerle P A, et al. (1996) Cell 87:13-20. Haskill S, et al. (1991) Cell 65:1281-1289.
Additional Text
Antibody Clonality
Polyclonal
Application Notes
Predicted MW: 120 kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
35-1372 Datasheet
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