Polyclonal Antibody to NF-kB-p100/p52 (Ab-870)
Catalogue Number: 35-1373-ABO
35-1373 Image
35-1373 Image
35-1373 Image
Figure 1: Western blot analysis of extracts from HL60 cells using NF-kB-p100(Ab-870) Antibody 35-1373 .
35-1373 Image
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NF-kB-p100(Ab-870) Antibody 35-1373 (left) or the same antibody preincubated with blocking peptide(right).
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | DNA-binding factor KBF2|| H2TF1|| Lymphocyte translocation chromosome 10|| Lyt10|| NF-kB2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide sequence around aa.868~872 (Y-G-S-Q-S) derived from Human NF-kB-p100. |
| Application: | WB, IHC |
Description
Description: NF-kB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NF-kB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. Qu Z, et al. (2004) J Biol Chem; 279(43): 44563-72. Xiao G, et al. (2001) J Biol Chem 7(2): 401-9.
Additional Text
Antibody Clonality
Polyclonal
Application Notes
Predicted MW: 120 kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
35-1373 Datasheet
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