Polyclonal Antibody to DNA PKcs (Ab-2609)
Catalogue Number: 35-1521-ABO
| Manufacturer: | Abeomics |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | DNPK1|| PRKD|| PRKDC|| XRCC7|| P460 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide sequence around aa.2607~2611 (V-E-T-Q-A) derived from Human DNA-PK. |
| Application: | WB |
Description
Description: The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties
Additional Text
Gene Name
PRKDC
Gene ID
5591
Uniprot ID
P78527
Antibody Clonality
Polyclonal
Application Notes
Predicted MW: 450kd, Western blotting: 1:500~1:1000
Storage Note
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
35-1521 Datasheet
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