Polyclonal Antibody to DNA PKcs (Ab-2609)

Catalogue Number: 35-1521-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:DNPK1|| PRKD|| PRKDC|| XRCC7|| P460
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide sequence around aa.2607~2611 (V-E-T-Q-A) derived from Human DNA-PK.
Application: WB

Description

Description: The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties

Additional Text

Gene Name

PRKDC

Gene ID

5591

Uniprot ID

P78527

Antibody Clonality

Polyclonal

Application Notes

Predicted MW: 450kd, Western blotting: 1:500~1:1000

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.