Polyclonal Antibody to OCT4

Catalogue Number: 35-1678-ABO

Manufacturer:Abeomics
Type:Polyclonal Primary Antibody - Unconjugated
Alias:Otc3|| OTF3|| OTF4|| OTF-3
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide sequence around aa.232~236 (R-K-R-T-S) derived from OCT-4
Application: WB

Description

Description: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency Pesce, M. and Scholer, H.R. (2001) Stem Cells 19, 271-278. Pan, G. and Thomson, J.A. (2007) Cell Res 17, 42-9. Cauffman, G. et al. (2006) Stem Cells 24, 2685-91.

Additional Text

Gene ID

5460

Gene Name

POU5F1

Uniprot ID

Q01860

Antibody Clonality

Polyclonal

Application Notes

Predicted MW: 45kd, Western blotting: 1:1000

Storage Note

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.