Mouse Monoclonal Antibody to Nivolumab (Clone : 8G6G3D8)

Catalogue Number: 45-1086-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 40 ug
Host name: Mouse
Clone: 8G6G3D8
Isotype: IgG1
Immunogen: Nivolumab
Application: ELISA

Description

Description: Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Anti-Nivolumab Antibody (8G6G3D8), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Nivolumab.

Additional Text

Purification

Protein A purified

Antibody Clonality

Monoclonal

Storage Note

The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Application Notes

ELISA detection: 0.01-0.1 µg/ml