Biotinylated Rabbit Monoclonal Antibody to Pembrolizumab (Clone : 90G12F8)

Catalogue Number: 45-1088-ABO

Manufacturer:Abeomics
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 40 ug
Host name: Rabbit
Clone: 90G12F8
Isotype: IgG
Immunogen: Pembrolizumab
Application: ELISA

Description

Description: Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Anti-Pembrolizumab Antibody (90G12F8)[BIOTIN], mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Pembrolizumab.

Additional Text

Purification

Protein A purified

Antibody Clonality

Monoclonal

Storage Note

The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Application Notes

ELISA detection: 0.01-0.1 µg/ml ELISA blocking: 10-50 µg/ml