Biotinylated Rabbit Monoclonal Antibody to Pembrolizumab (Clone : 90G12F8)
Catalogue Number: 45-1088-ABO
45-1088 Image
45-1088 Image
45-1088 Image
Figure-1 : ELISA binding of Pembrolizumab antibody (Clone: 90G12F8) binds with Pembrolizumab, Coating antigen: Pembrolizumab at 1 µg/ml Anti-Pembrolizumab antibody dilution start from 1,000 ng/ml,EC50= 5.01 ng/ml.
45-1088 Image
Figure-2 : ELISA blocking of Pembrolizumab antibody (Clone: 90G12F8) on Pembrolizumab and binding with Human PD-1 recombinant protein. Coating antigen: Pembrolizumab, 1 µg/ml. PD 1-Fc-biotin final concentration: 20 ng/ml. Anti-Pembrolizumab antibody dilution start from 10 µg/ml.IC50= 0.38 µg/ml.
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 40 ug |
| Host name: | Rabbit |
| Clone: | 90G12F8 |
| Isotype: | IgG |
| Immunogen: | Pembrolizumab |
| Application: | ELISA |
Description
Description: Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Anti-Pembrolizumab Antibody (90G12F8)[BIOTIN], mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Pembrolizumab.
Additional Text
Purification
Protein A purified
Antibody Clonality
Monoclonal
Storage Note
The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Application Notes
ELISA detection: 0.01-0.1 µg/ml ELISA blocking: 10-50 µg/ml
45-1088 Datasheet
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