Biotinylated Rabbit Monoclonal Antibody to Bevacizumab/Avastin (Clone : 46E3)
Catalogue Number: 45-1117-ABO
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45-1117 Image
45-1117 Image
45-1117 Image
Figure-1 : ELISA binding of Biotin conjugated Bevacizumab Antibody (Clone: 46E3) with Bevacizumab, Coating antigen: Bevacizumab at 1 µg/ml, Bevacizumab antibody dilution start from 2,000 ng/ml, EC50= 4.421 ng/ml.
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Figure-2 : ELISA Blocking of Biotin conjugated Bevacizumab Antibody (Clone: 46E3) with Vascular Endothelial Growth Factor 165 (VEGF 165), Coating antigen: Bevacizumab at 0.3 µg/ml, Anti-Bevacizumab Antibody (Clone: 46E3)final concentration: 8 ng/ml, VEGF 165 dilution start from 20 µg/ml, IC50= 46.16 ng/ml.
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Figure-3 : Standard curve of Bevacizumab Sandwich ELISA, The Bevacizumab Sandwich ELISA assay is developed by using Bevacizumab Antibody (Clone: 30E1)and Biotin conjugated Bevacizumab Antibody (Clone: 46E3) as the capture and detection antibodies respectively, The sensitivity of detecting Bevacizumab is up to 20 pg/ml.
| Manufacturer: | Abeomics |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 40 ug |
| Host name: | Rabbit |
| Clone: | 46E3 |
| Isotype: | IgG |
| Immunogen: | Bevacizumab |
| Application: | ELISA |
Description
Description: Bevacizumab (Avastin) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with colon cancer, lung cancer, glioblastoma, renal-cell carcinoma, and age-related macular degeneration. As an angiogenesis inhibitor, Bevacizumab blocks angiogenesis by inhibiting vascular endothelial growth factor A (VEGF-A).
Additional Text
Purification
Protein A purified
Antibody Clonality
Monoclonal
Storage Note
The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Application Notes
ELISA detection: 0.01-0.05 µg/ml
45-1117 Datasheet
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