6-OG488 acid [equivalent to Oregon Green® 488 carboxylic acid, 6-isomer]
Catalogue Number: 712-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 12 months |
| Type: | Fluorophores |
| Shipping Condition: | RT |
| Unit(s): | 25 mg |
Description
Description: 6-OG488 acid is the same molecule to Oregon Green® 488 carboxylic acid, 6-isomer (Oregon Green® is the Trademark of Invitrogen). This fluorinated analog of fluorescein has higher photostability and a lower pKa ~ 4.7 while 6-FAM has pKa ~6.4. The decreased pKa of 6-OG488 makes its fluorescence essentially pH insensitive in the physiological pH range. This amine-reactive 6-OG488 can be used to make bright green fluorescent bioconjugates with excitation/emission maxima ~496/524 nm. It is an excellent replacement to 6-FITC that has severe pH dependence and low photostability.
Additional Text
Storage Note
Freeze (< -15 °C); Minimize light exposure;|12 months
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