Cy3.5 azide (non-sulfonated)

Catalogue Number: A8112-APE

Manufacturer:	Apexbio
Shelf Life:	24 months
Molecular Formula:	C44H53ClN6O
Physical state:	A solid
Type:	Click Chemistry Reagent
Shipping Condition:	Blue Ice
Unit(s):	25 mg, 5 mg

Overview
Datasheets

Description

Description: Cy3.5 azide is a solid material dye ready for the use in Click Chemistry reaction. Most derivatives of non-sulfonated cyanines have low aqueous solubility except for hydrochlorides of hydrazides and amines. For biomolecule labeling, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. Cy3.5 azide could easily interfere with a radical polymerisation process as it contains a variety of double bonds. The Cy-3 modified initiator was then used to grow the modified PMPC-PDPA directly from the dye [1].Reference:[1] Gaitzsch, J.; Delahaye, M.; Poma, A.; Du Prez, F.; Battaglia, G. Comparison of metal free polymer-dye conjugation strategies in protic solvents. Polymer Chemistry, 2016, 7(17), 3046-3055.

Additional Text

Short Description

used for Click chemistry to label alkyne-modified oligonucleotides

Reagent:Smile String

CC1(C)C2=C3C(C=CC=C3)=CC=C2[N+](CCCCCC(NCCCN=[N+]=[N-])=O)=C1/C=C/C=C4C(C)(C)C5=C(C=CC=C6)C6=CC=C5N4CCCC

Solubility

≥71.7 mg/mL in DMSO; insoluble in H2O; ≥44.2 mg/mL in EtOH with ultrasonic

Storage Note

24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Price

£1,080.00

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