Cy5.5 azide (non-sulfonated)

Catalogue Number: A8114-APE

Manufacturer:	Apexbio
Shelf Life:	24 months
Molecular Formula:	C43H49ClN6O
Physical state:	A solid
Type:	Click Chemistry Reagent
Shipping Condition:	Blue Ice
Unit(s):	25 mg, 5 mg

Overview
Datasheets

Description

Description: This Cy5.5 is a labeling reagent that ready for the use in Click Chemistry reaction which available as 10 mM solution in DMSO. As Cy5.5 azide is a far-red emitting dye, it can replace Alexa Fluor 680, and DyLight 680. Most derivatives of non-sulfonated cyanines have low aqueous solubility except for hydrochlorides of hydrazides and amines. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. In human glioblastoma U87MG cells, to assess the capability of the Cu(I)/M-dots for cell labeling Cy5.5-azide was in combination with Cu(I)/M-dots for imaging of the integrin αVβ3 receptor [1].Reference:[1] Sun, Y.; Hong, S.; Ma, X.; Cheng, K.; Wang, J.; Zhang, Z.; Yang, M.; Jiang, Y.; Hong, X.; Cheng, Z. Recyclable Cu(I)/Melanin Dots for Cycloadditions, Bioconjugation and Cell Labeling. Chemical Science.

Additional Text

Short Description

used for Click chemistry to label alkyne-modified oligonucleotides

Reagent:Smile String

CC1(C)C2=C3C(C=CC=C3)=CC=C2[N+](CCCCCC(NCCCN=[N+]=[N-])=O)=C1/C=C/C=C/C=C4C(C)(C)C5=C(C=CC=C6)C6=CC=C5N4C.[Cl-]

Solubility

≥70.1 mg/mL in DMSO; insoluble in H2O; ≥46.2 mg/mL in EtOH with ultrasonic

Storage Note

24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Price

£1,080.00

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