Cy7 azide (non-sulfonated)

Catalogue Number: A8115-APE

Manufacturer:Apexbio
Shelf Life:24 months
Molecular Formula:C40H51ClN6O
Type:Click Chemistry Reagent
Shipping Condition:Blue Ice
Unit(s): 25 mg, 5 mg

Description

Description: Cy7 azide is a labeling reagent that ready for the use in Click Chemistry labeling. This labeling dye is a near-infrared dye which has low aqueous solubility. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecules is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer. This product can be used for the incorporation of Cy7 azide into various biomolecules and post-synthetic modification of oligonucleotides is also available. PEG-b-PPLG-Cy7 was conjugated by Cy7 azid and the polymer of PEG-b-PPLG. In blank micelles, it was used to probe the association of unimers [1].Reference:[1] Morton, S.W.; Zhao, X.; Quadir, M.A.; Hammond, P.T. FRET-enabled biological characterization of polymeric micelles. Biomaterials,2014, 35(11), 3489-3496.

Additional Text

Short Description

used for Click chemistry to label alkyne-modified oligonucleotides

Solubility

soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water

Reagent:Smile String

CC1(C2=CC=CC=C2[N+](=C1C=CC3=CC(=CC=C4C(C5=CC=CC=C5N4CCCCCC(=O)NCCCN=[N+]=[N-])(C)C)CCC3)C)C

Storage Note

24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.