Catalogue Number: A8265-APE
Manufacturer: | Apexbio |
Molecular Formula: | C30H40Cl2N4O |
Physical state: | A solid |
Type: | Fluorescent Reagents |
Shipping Condition: | Blue Ice |
Unit(s): | 1 mg, 25 mg, 5 mg, 50 mg |
Description: Cy3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide. Cyanine3 dyes have been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. They are widely used for labeling peptides, proteins and oligos etc.Cy3 hydrazide can be used to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone deamination or oxidative stress, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments. References:Pan D, Qin H, Cooperman BS. Synthesis and functional activity of tRNAs labeled with fluorescent hydrazides in the D-loop. RNA. 2009 Feb;15(2):346-54.Tamarit J, de Hoogh A, Obis E, et al. Analysis of oxidative stress-induced protein carbonylation using fluorescent hydrazides. J Proteomics. 2012 Jun 27;75(12):3778-88.Kameyama A, Kaneda Y, Yamanaka H, et al. Detection of oligosaccharides labeled with cyanine dyes using matrix-assisted laser desorption/ionization mass spectrometry. Anal Chem. 2004 Aug 1;76(15):4537-42.
Store at -20°C
carbonyl-reactive dye
CN1C2=CC=CC=C2C(C)(C)/C1=CC=CC3=[N+](CCCCCC(NN)=O)C4=CC=CC=C4C3(C)C.[Cl-].Cl
≥54.4 mg/mL in DMSO; ≥48.2 mg/mL in EtOH; ≥50.8 mg/mL in H2O