Catalogue Number: ABM0043-ABK
Manufacturer: | Abbkine |
Shelf Life: | 12 months |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Mouse |
Clone: | |
Isotype: | IgG1 |
Immunogen: | Synthetic Peptide |
Application: | WB |
Description: PARP1 encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, poly (ADP-ribose) polymerase 1 may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
PARP1
P09874
1 mg/ml
142
Affinity Purified
Monoclonal
Mouse Anti-Cleaved PARP Monoclonal Antibody
116, 89 KD