mAb35-SAP Kit
Catalogue Number: BETA-034-ATS
| Manufacturer: | Advanced Targeting Systems |
| Preservative: | No preservative |
| Type: | ZAP Conjugate |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 ug |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: This targeted toxin recognizes cells that express nicotinic acetylcholine receptors. mAb-SAP is a chemical conjugate of mAb35 and the ribosome-inactivating protein, saporin. This antibody binds to nicotinic acetylcholine receptors (nAChR) in several species, including human and rat. The antibody was originally raised against the electric organ of Electrophorus electricus and produces experimental autoimmune myasthenia graves. mAb 35 cross-reacts with muscle-type and some neuronal nAChRs. It reacts with a single epitope in a1, a3, and a5 subunits of nAChR.
Additional Text
Usage Information
mAb35-SAP eliminates cells expressing the nicotinic acetylcholine receptors (nAChR). All other cells are left untouched.
Short Description
a tool for eliminating cells that express nicotinic acetylcholine receptors (nAChR); targeted via mAb35 and eliminated via saporin
BETA-034 Datasheet
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