Catalogue Number: BS-0186R-CY5-BSS
Manufacturer: | Bioss Inc |
Type: | Polyclonal Primary Antibody - Conjugated |
Alias: | IRS1--Insulin receptor substrate-3; IRS3; IRS-3; IRS3. |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | KLH conjugated synthetic peptide derived from rat IRS-3 |
Application: | ICC, IF, IHC-P, WB, IHC-Fr |
Description: The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. IRS-1 may mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2.
Protein A purified
1 ug/ul
Polyclonal
84021
Irs3
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.