Catalogue Number: BS-0215R-BSS
Manufacturer: | Bioss Inc |
Shelf Life: | 12 months |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | lpr; APO1; APT1; CD95; TNFR6; Tnfrsf6; AI196731; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; Fas |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 20 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | KLH conjugated synthetic peptide derived from mouse FAS |
Application: | ELISA, FC, ICC, IF, IHC-P, WB, IHC-Fr |
Description: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity).
FAS
P25446
14102
Protein A purified
1 ug/ul
Polyclonal
Unmodified
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.