Catalogue Number: BS-1100R-BSS
Manufacturer: | Bioss Inc |
Shelf Life: | 12 months |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | FAT; GPIV; Scarb3; Platelet glycoprotein 4; Glycoprotein IIIb; GPIIIB; PAS IV; PAS-4; Platelet glycoprotein IV; CD36 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 20 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | KLH conjugated synthetic peptide derived from mouse CD36 |
Application: | ELISA, IHC-P, WB |
Description: Binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport (By similarity). Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects (By similarity). As a coreceptor for TLR4-TLR6, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42 binding, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory signals, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.
12491
Q08857
CD36
Protein A purified
1 ug/ul
Polyclonal
Unmodified
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.