Catalogue Number: BS-1799R-BSS
Manufacturer: | Bioss Inc |
Shelf Life: | 12 months |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | GLUR3; GLURC; GluA3; MRX94; GLUR-C; GLUR-K3; Glutamate receptor 3; GluR-3; AMPA-selective glutamate receptor 3; Glutamate receptor ionotropic, AMPA 3; GRIA3 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 20 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | KLH conjugated synthetic peptide derived from human GLUR3 |
Application: | ELISA, FC, ICC, IF, IHC-P, IHC-Fr |
Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
GRIA3
P42263
2892
Protein A purified
1 ug/ul
Polyclonal
Unmodified
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.